Vitamin

Vitamin k2 7

Vitamin K2-7, also called menaquinone-7 or MK-7, activates specific proteins through a process called carboxylation. These proteins include osteocalcin, which is involved in bone mineral metabolism.

Its longer circulating half-life supports a practical role alongside calcium, vitamin D and magnesium in bone-focused formulas.

In everyday life, Vitamin K2-7 helps activate the proteins that support appropriate calcium handling and the ongoing maintenance of healthy bones.

People taking vitamin K antagonist medicines should consult a healthcare professional.

Available in

1 product

Bonemax

Ingredient overview

What it is

Vitamin K2-7, also called menaquinone-7 or MK-7, activates specific proteins through a process called carboxylation. These proteins include osteocalcin, which is involved in bone mineral metabolism.

  • Scientific identity: Vitamin K2-7; molecule: Menaquinone-7, seven isoprenoid units.
  • How it works: Produced by fermentation: Menaquinone-7 is made by bacterial fermentation and carries a side chain of seven isoprenoid units. Absorbed with fat and carried on lipoproteins: Its long, lipid-friendly tail keeps it circulating rather than clearing quickly.
  • Primary function: Its longer circulating half-life supports a practical role alongside calcium, vitamin D and magnesium in bone-focused formulas.
  • What it supports: Vitamin K2-7 helps activate the proteins that support appropriate calcium handling and the ongoing maintenance of healthy bones.
  • Important consideration: People taking vitamin K antagonist medicines should consult a healthcare professional.

Formulation rationale

Why we use it

CARPEDIEM selected Vitamin K2-7 for a clearly defined role within a thoughtfully balanced formulation.

  • Formulation purpose: Its longer circulating half-life supports a practical role alongside calcium, vitamin D and magnesium in bone-focused formulas.
  • Used in: CARPEDIEM BoneMax and CARPEDIEM Women’s Bone & Daily Wellness Stack.
  • Works alongside: Vitamin K2-7 complements Vitamin D3, Magnesium and Boron to support comprehensive daily nutritional support.
  • Meaningful contribution: Vitamin K2-7 helps activate the proteins that support appropriate calcium handling and the ongoing maintenance of healthy bones. Provides menaquinone-7, a vitamin K2 form with a comparatively long circulating half-life.
  • Quality and scientific context: People taking vitamin K antagonist medicines should consult a healthcare professional. 4 ingredient-specific studies are included because the research reports a relevant benefit.

Ingredient intelligence

How it works

The vitamin K form whose long tail keeps it in the blood for days.

Step 01 / 04

Made by fermentation.

Menaquinone-7 is produced by bacterial fermentation and carries a tail of seven repeating units.

01 / 04

Molecule

Menaquinone-7 (MK-7)

Half-life

~3 days, against hours for MK-4

Activates

Osteocalcin and matrix Gla protein

Typical dose

90 to 180 mcg

Descriptive of the ingredient's established biology. Not a claim to diagnose, treat, cure or prevent any disease.

Functional role

All key functions

The complete functional profile connected with this ingredient.

Supports the activation of osteocalcin, a protein involved in normal bone mineralisation.

Contributes to the maintenance of healthy bones alongside calcium and vitamin D.

Provides menaquinone-7, a vitamin K2 form with a comparatively long circulating half-life.

Supports the normal biological activity of vitamin K-dependent proteins.

Contributes to normal blood coagulation through recognised vitamin K pathways.

Helps connect calcium-focused nutrition with the proteins involved in bone metabolism.

Helps activate the proteins that support appropriate calcium handling and the ongoing maintenance of healthy bones.

Complements Vitamin D3 and Calcium within a more complete, scientifically balanced daily formulation.

Scientific evidence

Selected research

Open the original paper, PubMed record or DOI page for the full publication.

01

Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women

Osteoporosis International

244 healthy postmenopausal women, 180 micrograms of MK-7 a day, three years. The finding that matters is in the timing: through the first year, bone loss looked the same in both groups. Only over the full three years did the MK-7 group show significantly less age-related decline in bone mineral density and bone strength than placebo. It is the study that explains why short vitamin K trials kept coming back empty — and why bone nutrition is measured in years, not weeks.
2013
02

Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women

Osteoporosis International

A three-year randomized placebo-controlled trial evaluated low-dose menaquinone-7 in healthy postmenopausal women and reported benefits in selected measures of vitamin K status and bone health. The findings are relevant to MK-7 specifically and to the studied population.
2013
03

Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial

Thrombosis and Haemostasis

A long-term randomized trial in healthy postmenopausal women evaluated MK-7 and reported improvement in selected measures of arterial stiffness, especially among participants with higher baseline stiffness. The finding is population-specific and does not establish a general cardiovascular treatment claim.
2015
04

The effect of menaquinone-7 (vitamin K2) supplementation on osteocalcin carboxylation in healthy prepubertal children

British Journal of Nutrition

This double-blind randomized placebo-controlled trial found that eight weeks of MK-7 improved osteocalcin carboxylation in healthy children. It supports vitamin K-dependent protein biology but does not establish a fracture-prevention benefit.
2009
05

Olive oil supplemented with menaquinone-7 significantly affects osteocalcin carboxylation

This controlled human study evaluated MK-7 delivered in olive oil and measured changes in osteocalcin carboxylation. It provides supporting evidence for MK-7 bioactivity in a food-based delivery system.
2011

In your routine

Products containing Vitamin k2 7

Explore the Carpediem formulations connected with this ingredient.

Bonemax

Carpediem formula

Bonemax

Rs. 649.00

View product →

Related ingredients

Complementary by function

Vitamin

Vitamin d3

Mineral

Calcium

Mineral

Magnesium

Mineral

Boron

Ingredient intelligence

How it works

The vitamin K form whose long tail keeps it in the blood for days.

Step 01 / 04

Made by fermentation.

Menaquinone-7 is produced by bacterial fermentation and carries a tail of seven repeating units.

01 04

Molecule

Menaquinone-7 (MK-7)

Half-life

~3 days, against hours for MK-4

Activates

Osteocalcin and matrix Gla protein

Typical dose

90 to 180 mcg

Descriptive of the ingredient's established biology. Not a claim to diagnose, treat, cure or prevent any disease.